Tuesday, June 2, 2020

GERMOPHOBE'S PARADISE & THE BOOM OF THE SANITIZING MARKET

by: Robert L. Bard, MD

In the era of Covid, where fighting invisible airborne killers are recognized as our new global reality, we call on the scientific community to offer logical innovations to thwart the pandemic issue.  While a vaccine for the Coronavirus remains in research phase, our battle leans heaviest in targeting prevention, safety and protection protocols.

As we continue to reach new levels of "the curve", businesses and industries continue to suffer the economic downturn while a select group are receiving the BOOM of a lifetime.  Such is the case for web-based technologies (temporarily replacing social gathering), PPE manufacturers, pharmaceuticals and the many marketers of SANITIZING PRODUCTS.

As market trends are aligned with consumer behavior, the March lock-down prompted panic-shopping and premature hording frenzy.  This led to empty shelves nationwide, further raising the level of desperate consumer activity.  But recent signs are showing a strong rebound of fulfillment activity in stores with a re-growing supply of many health essentials.

Manufacturers old and new are fast responding to the consumer's emotion-based reactive shopping behavior.  Domestic popular brands and generic house brand producers (white label manufacturers) are now showing increased presence in retail store shelves with more stores finding little need to limit customers from over-buying. The War Powers Resolution Act has been said to help motivate new American suppliers and producers by expanding their product lines to include creating PPE's and other health & sanitizing products.

...BUT WHAT ARE THEY SELLING US?
In the case of marketing sanitizers, a phrase like "Kills 99.9% of bacteria " is one of the most common sell-phrase used to describe antimicrobial or antiseptic products. Others brandish even more pointed descriptions like germicidal, fungicidal, virucidal, or (even) tuberculocidal to paint an even higher scientific picture to lure buyers.   A wise word of caution to consumers is to READ the active ingredient in all these packages as part of recognizing exactly what we are exposing ourselves to-  and knowing how they can affect us.

Fact: Not all sanitizers are the same!  Types of  ANTIMICROBIAL SANITIZERS on the market fall into one of five base categories: alcohol, chlorine (bleach), phenol, quarternary amine and quarternary amine + alcohol. (The effects of these chemicals and their potential health effects will be discussed in part 2 of this report.)

* Benzalkonium Chloride
* Isopropyl Alcohol
* Ethyl Alcohol (ethanol)
* sodium hypochlorite
* Didecyldimethylammonium Chloride
* Alkyl Dimethyl Benzyl Ammonium Saccharinate

COMMERCIAL SANITIZING: PREVENTION OR MAINTENANCE
Entering the warmer months of 2020, we are all (by now) programmed by prevention to wash our hands incessantly, mask up in all public and shared areas and "think contagion" when touching just about anything.  Where health means supporting our immune system to fight off any bacteria or virus,  this fight also means stepping up our cleaning practices to stricter measures like sanitizing , disinfecting and sterilizing of our homes and work areas.

For commercial areas, an influx of cleaning companies are majorly promoting "disinfecting services for covid".  The industry term HAI (healthcare-associated infections) is often used in healthcare and hospitals to apply to disinfecting solutions and sanitizing standards.  Upon review of some of the top advertised service providers, certain products and sanitizing protocols are offered to manage HAI rates.

These products are either "fogged" in an enclosed space, sprayed on contact with an "electrostatic applicator" or wiped on surfaces.  One common product is called Noroxycdiff - a hospital grade, EPA registered disinfectant for use against SARS-CoV-2. The main active ingredient in our chemical is Hydrogen Peroxide. Another is BIOCIDE 100, a product used for remediating mold. Meanwhile other companies offer applying VITAL OXIDE through an Electrostatic Sprayer or hospital grade wipes like CLOROX HEALTHCARE VERSASURE or OXIVIR wipes.  

Other products are also trending on the market like Nano-wipes including the common brand "Bio-Kil" used in high-demand areas such as ICU. "After application of Bio-Kil, the bacterial burden declined in both groups, although the reduction was greater in the study rooms as compared with the control rooms (p = 0.001). During the pre-intervention period, 16 patients were admitted to control rooms and 18 patients to study rooms. After the intervention, 22 patients were admitted to control rooms and 21 patients to study rooms. The number of cases of new-onset sepsis declined in the intervention group (from 33% to 23.8%), but increased in the control group (from 25% to 40.9%); however, there was no significant difference in incidence of new-onset sepsis between the study and control rooms after intervention. Application of Bio-Kil reduced the environmental bacterial burden and MDROs in ICUs. Further studies are needed to evaluate the efficacy of this nanotechnology-based disinfectant in reducing HAIs. [2]|

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SANITIZING WITH UV-C LIGHT
In a recent interview with American Health Supply Co. (a PPE supplier), a unique concept of using ultraviolet light to disinfect surgical and respiratory masks for repeated use extends the life of what is currently a rare, life-saving commodity.

Hospitals that use UV-light disinfection after cleaning and disinfection standard protocol have actually significantly mitigated infection risks associated with environmentally mediated transmission routes. [6]  Investigations of the bactericidal effect of sunlight in the late 19th century planted the seed of air disinfection by UV radiation. First to nurture this seed was William F. Wells, who both discovered the spread of airborne infection by droplet nuclei and demonstrated the ability of UVGI to prevent such spread. Despite early successes in applying UVGI, its use would soon wane due to a variety of reasons that will be discussed in this article. However, with the enduring research of Riley and others, and an increase in tuberculosis (TB) during the 1980s, interest in UVGI was revitalized. With modern concerns regarding multi- and extensive drug-resistant TB, bioterrorism, influenza pandemics, and severe acute respiratory syndrome, interest in UVGI continues to grow. Research is ongoing, and there is much evidence on the efficacy of UVGI and the proper way to use it, though the technology has yet to fully mature. [5]

Dr. Christopher Centeno of Regenexx, a prominent stem cell therapy center in Boulder, Colorado subscribes to the benefits of UV-C disinfectant lighting. “Our clinic began researching UVC light sterilizers about two months ago, but they were very expensive and hard to get. Hence, I decided to build my own. This project cost $400 with parts from Amazon that took a week to get. The average commercial price of an exam room sterilizer is about $5,000 and these take months to be delivered after ordering.  I’ve tested our DIY unit with standard UV dosimeter cards used in hospitals and it pumps out enough UVC light to kill MRSA.”

An early study showed that NAIs caused a significant amount of biological decay of the bacterium Serratia marcescens. Exposure to NAIs showed inactivation or growth inhibition of the bacteria E. coli, Candida albicans, Staphylococcus aureus, P. fluorescens [96,97,98,99,100] and has a lethal effect on starved Pseudomonas veronii cells. NAIs prevented 60% of tuberculosis (TB) infection and 51% of TB disease. Except for the inhibition effect of NAIs on bacteria, reports also showed that NAIs inhibited the growth of fungi and viruses. (Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213340/)

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PREVENTION 1: IMMUNE SYSTEM SUPPORT
By: Dr. Jesse A. Stoff


Basic biology attributes any contracted sickness or disease to a WEAKENED and COMPROMISED IMMUNE SYSTEM.   Our body's immune system accounts for approximately 1% of the body's 100 trillion cells.  The different cell lineages that develop all share one common objective: to identify and destroy all substances (living or inert) which are recognized as not being part of what "should be in the body.” Whether it is an abnormal cell or what are perceived as dangerous or damaged cells, they are actively hunted down and destroyed by effector cells of the immune system.

Imagine having your own personal army of cells in your highly advanced defense system, working against outside invaders or abnormal cells where each cell type (over one hundred and eighty-seven recorded) carries their own dedicated function. This specialized team of cells work together to fulfill the complex mission of protecting the body from infection or illness each day.

During this (and any) pandemic, supporting and boosting the immune system is priority 1. Improving the health of the immune system means your body will become more resistant to incoming diseases. Making your immune system stronger is not a linear program, because you are dealing with a complex network of factors in your body that needs to be addressed. However, there are certain measures you can take to boost the immune system.  If you have to do one thing to boost your immune system, it should be maintaining a healthy lifestyle because there is no better and natural way for the improvement of the immune system. Avoid smoking, eat healthy, limit your alcohol consumption, maintain your weight and blood pressure, and get enough sleep.

Make sure that you are consuming all those important micronutrients which are important for bolstering the immune system. If you can’t manage this through your diet alone, go for supplements.  Vitamin D is often referred to as the sunshine vitamin because our body can actually manufacture vitamin D. It's a fat-soluble vitamin, and it's metabolized in our body from various fat-soluble steroid complexes, as they're referred to. And vitamin D is then metabolized in the skin and split from some of these molecules into the active form of vitamin D- which then has a wide range of effects on basically every single cell in our body. Vitamin D isn't just about having strong bones and strong teeth; vitamin D also has some really wonderful effects from a preventative medical point of view.
(For complete articles on the immune system, visit Dr. Stoff's Immunology Today blogsite: http://immunologysmarts.com/)


Ref: 
1) A Comparison of Commonly Used Surface Disinfectants
https://www.infectioncontroltoday.com/environmental-hygiene/comparison-commonly-used-surface-disinfectants

2) Bio-Kil, a nano-based disinfectant, reduces environmental bacterial burden and multidrug-resistant organisms in intensive care units-  Journal of Microbiology, Immunology and Infection https://www.sciencedirect.com/science/article/pii/S168411821630038X

3) Silver nanoparticles as an effective disinfectant: A review (Pub med)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7127744/


4) Top ten disinfectants to control HAIs
https://www.hospitalmanagement.net/features/featureppc-disinfectants-hai-globaldata/

5) The History of Ultraviolet Germicidal Irradiation for Air Disinfection 

6) Evaluation of an Ultraviolet C (UVC) Light-Emitting Device for Disinfection of High Touch Surfaces in Hospital Critical Areas https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6801766/


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