Monday, July 6, 2020

COALITION OF GLOBAL SCIENTISTS IN SOLIDARITY TO SAVE LIVES

Collaborative Action Behind COVID-19 Tools R&D supported by The UN Foundation
By: Rachel Bridges-  Senior Global Health Advocacy and Communications Manager for the United Nations Foundation  |    Edited by: Prevention101.org


"The COVID-19 pandemic has demonstrated the interconnected nature of our world – and that no one is safe until everyone is safe.  Only by acting in solidarity can communities save lives and overcome the devastating socio-economic impacts of the virus.  In partnership with the United Nations, people around the world are showing acts of humanity, inspiring hope for a better future." - The United Nations, We’re All in This Together. 

Photo credit: Institut Pasteur (courtesy of the UN Foundation)
The United Nations Foundation (UN Foundation) is one of the fiduciary partners behind the COVID-19 Solidarity Response Fund for the World Health Organization (WHO).  The foundation supports WHO and partners’ efforts to prevent, detect, and respond to the global COVID-19 pandemic around the world, especially in vulnerable areas. The Coalition for Epidemic Preparedness Innovations (CEPI), an organization helping to lead the discovery of potential COVID-19 vaccines, received a $10 million disbursement through the Fund to help catalyze and coordinate global vaccine research and development. The UN Foundation also works closely with the WHO, and other partners, to help share the most up-to-date scientific information with the public about COVID-19 which WHO generates and amplifies through its global coordination of the COVID-19 response.

 While research developments are still in early stages, we are seeing the fastest R&D efforts in human history unfold. Through WHO’s leadership, a genetic sequence of the novel coronavirus (COVID-19)—a previously unknown disease—was shared with the world just 2 weeks after its initial discovery. Through coordinated efforts led by WHO, research and development is rapidly moving forward so that everyone, everywhere can have access to tools to help prevent, detect, and respond to COVID-19. Some examples of these efforts include:
    Photo credit: University of Queensland (courtesy
    of  the UN Foundation)
  • WHO’s global Solidarity Trial aims to rapidly develop an effective treatment for COVID-19. As of mid-August 2020, the Solidarity Trial has more than 3500 patients enrolled with more than 100 countries participating, including more than 400 hospitals in 35 countries alone. According to the WHO, the Solidarity Trial will reduce the amount of time it normally takes for a drug trial to determine effectiveness by 80%. This, combined with the size and geographic breadth of the trial, will provide a strong evidentiary basis behind specific therapies that can then be acted upon quickly by health systems.
  • WHO has published a research and development roadmap, with a set of protocols for how studies should be done to create potential therapeutics or vaccines. 
  • WHO is already working with scientists across the globe on over 120 different candidate vaccines for coronavirus with eight already in clinical trials in record time — just a few months after sequencing the gene.
  • 10 vaccine candidates in clinical evaluation and 123 in pre-clinical evaluation
In addition to the R&D work WHO and the Fund are helping to support, resources through the Solidarity Response Fund are helping to supply critical personal protective equipment, biomedical supplies, and infection prevention and control measures for vulnerable populations like refugees and displaced people.

Photo credit: UNICEF
Photo credit: UNICEF
As a global effort, donors from more than a 190 countries generously gave to COVID-19 relief efforts through the COVID-19 Solidarity Response Fund. These resources are also helping to support countries around the world get vital information to help protect communities, as well as critical supplies to help prevent, detect, and respond to this global pandemic. As of the beginning of August 2020, WHO has shipped more than 200 million items of personal protective equipment and more than 5.6 million pieces of testing equipment to more than 130 countries. The Fund also supports the work of the World Food Programme, the UN refugee agency (UNHCR), UNICEF, and the United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) to work in many vulnerable countries and settings including Bangladesh, Syria, Lebanon, Jordan, Gaza, Kenya, and South Sudan to support at-risk refugee or displaced populations. You can learn more about the Fund’s impact here.

The UN Foundation helps support COVID-19 treatment research through mobilizing resources via the COVID-19 Solidarity Response Fund, as well as supporting WHO and partners working to discover COVID-19 treatments through advocacy and communications efforts with policy makers, global funders, and the general public. We help share scientific information as its being discovered, as well as advocate for continued investments in this critical research and development efforts being coordinated by WHO and global partners like UNITAID, the Global Fund, and others through the ACT Accelerator. 

WHO plays a critical role in coordinating a range of global health initiatives, including the global response to COVID-19. To this point, it has served as the global coordinator of efforts to develop vaccines, tests and treatments; trained millions of health workers; distributed millions in medical supplies, while also continuing the fight against other major health threats that matter to Americans like malaria, measles, and HIV/AIDS.

Currently, WHO’s efforts and the global COVID-19 response are undergoing challenges due to political challenges between member states. However, WHO’s global scientific research initiatives continue to forge ahead toward its imperative to resolve the pandemic. Only though coordinated and collaborative action can we stop this virus for everyone, everywhere. To help support WHO and partners’ global COVID-19 response, visit the COVID-19 Solidarity Response Fund website.

ABOUT THE AUTHOR:
Rachel Bridges is passionate about creating impactful communications to help foster global change in her role as the Senior Advocacy and Communications Manager for Global Health for the United Nations Foundation. Prior to her time at the United Nations Foundation, she worked on various global health issues, including HIV/AIDS, tuberculosis, and neglected tropical diseases for the U.S. Agency for International Development. She holds a Master of Public Health degree from Washington University in St. Louis and a B.A. in English and French, with a minor in Women’s and Gender Studies, from Furman University. 








GOING GLOBAL WITH NYCRA-NEWS
Feb. 27, 2021 - Health providers and educators at the European Pandemic front and Cancer Care societies, in support of global information sharing- aligned with NYCRA-NEWS, expressing complete support of a global health initiative. NYCRA-TV is forming international partnerships and alliances starting with our first Italian translated video of our top NYC cancer diagnostic expert Dr. Robert Bard with this trailer from his 2021 presentation on cancer diagnostic innovations. (SEE video clip). "This is the start of a collaborative union between countries to exchange information from our respected fields... and drive an inspired bond, presenting the best of what a global coalition of caregivers and scientists can bring!"- states a representative  of the upcoming program "Notizei Globali- IT (Global Health News) "

Dr. Robert Bard (US) presents a review on global advancements in Elastography, digital Pet/CT scans, MRI and the Doppler Ultrasound scanning.  As part of a medical seminar for the NY Cancer Resource Alliance and a list of cancer organizations, this educational overview supports the value of quantifiable readings that successfully reduce/prevent unnecessary biopsies and false positives. The movement to Integrate current cancer scanning modalities paves the way for a faster, and a more accurate way of tracking cancer aggression, allowing for the adjustment of therapies as needed in a timely manner. (Versions: ENGLISH | ITALIAN)


SCIENTIFIC ALLIANCES:  UNITED MINDS ON A COMMON MISSION
World medical conferences and international forums unite
multidisciplinary experts to continue global info-sharing

This pandemic has clearly illustrated that "Scientists by nature do not see borders or politics - only solutions", states Dr. Robert Bard, cancer diagnostics expert (NYC). "The spirit of teamwork is alive and well with this community- especially in a crisis. Historically, medical and scientific people have always raced to the front lines - always at the ready to pool resources and collaborate. Like the domestic and international health associations, we continue to see some of the sharpest clinical minds in the world- including American teams that are now coming out with promising protocols to help end this pandemic. To contain and eliminate this human threat means UNITING WITH SCIENCE AND WORKING TOGETHER ON A COORDINATED GOAL."

Such is the case with this remarkable grouping of like minds under a targeted objective. They call themselves The Front Line Covid-19 Critical Care Alliance - highly published critical care specialists from major academic medical centers with collectively over 1,000 medical publications.

Meet Some of the "Top Medical Minds in the Front Lines"
(Founding members & clinical advisors of MATH+ formed The Front Line Covid-19 Critical Care Alliance).

Based on the rapidly emerging research into COVID-19, the early clinical experience in China reflected by the Shanghai expert commission, and their decades-long clinical and research experiences in severe infectious diseases around the country, the 5 experts developed the MATH+ Hospital Treatment Protocol for Covid-19. It is intended for use early in the hospitalization of patients presenting with states of respiratory distress requiring supplemental oxygen. These 5 have since been joined by an increasing number of hospitalist and ICU physicians who recognize the sound physiologic rationale, the emerging published research in support of the components, and the data demonstrating good clinical outcomes in hospitals that have adopted the treatment regimen.

Methylprednisolone & MATH+: Treatment Success Data from the Nation's "HOT SPOTS"

With a confirmed global count of 9.27+ Million cases and 470,000+ deaths, the world continues its desperate search for a treatment that will save the lives of COVID-19 patients who come into the ER or hospital with low oxygen levels or struggling to breathe. Where the more popular treatment for patients in ICU is the use of ventilators, a reported 80-85% of Covid-19 patients on ventilators in New York end up dying (Associated Press and state and city officials).

The corticosteroid Methylprednisolone is a key component, based on large studies that have proven its effectiveness in prior viral pandemics‐ and whose potency is significantly increased when administered intravenously with high doses of the antioxidant Ascorbic acid (Vitamin C). Thiamine (Vitamin B1) is given to optimize cellular oxygen utilization and energy consumption, protecting the heart, brain, and immune system and the anticoagulant Heparin prevents (or breaks up) blood clots that increasingly appear as illness worsens. The + represents other supportive treatments by the administering doctor for patients who present other pre‐existing conditions (as needed). The group also plans to add or change components and dosing as published medical literature evolves.

LATEST UPDATES: According to physicians implementing the MATH+ Covid-19 treatment protocol, conclusive data shows significant success by as much as 97%, where only 3-6.6% mortality- from hospital reports including the VIRGINIA DEPT. OF HEALTH. (See complete report)

See LINK for complete "ESSENTIALS on MATH+ Covid-19 intervention protocols"


"MATH+ Saved my Life"- patient story

       

VIEWPOINTS
MEGAN MELLER, MS, MPH - Infection Control at Gundersen Health System
As soon as SARS-CoV-2 began generating international attention, I knew that the scientific community would rally. After working in a virus research lab for 3 years, I know that science and passion often go hand in hand. Collaboration is at the heart of research, especially successful research but it is also notoriously a slow and methodical process. Rushed science is often flawed, which is why peer-review and open access is so critical. … We live in historical times and pandemics set the stage for innovation (e.g. Solidarity Trial and Solidarity Response Fund). Most vaccine technology is the product of many years of hard work. International emergencies have a way of opening the peoples' eyes to fields that typically operate away from the worlds eyes (e.g. research, public health, Infection Control).

EPILOGUE:  Epidemiology

By: Lennard M. Gettz & Cheri Ambrose/ NY Cancer Resource Alliance

June 24, 2020- Months into the CoronaVirus pandemic, the tally of efforts expended by government health agencies and professionals worldwide has been noted to significantly exceed any global campaign in history.  Economists tend to use war terms to help put the pandemic's containment efforts and collateral damage in perspective.  IMF's chief economist Gita Gopinath,  (in an April 15 news conference) stated that "the best case scenario, the world is likely to lose a cumulative $9 trillion in output over two years"- making this a global war 3x the fiscal size of World War II.

As with past wars, alliances were formed, industries were committed to task and scientists worldwide have united by sharing information toward this single directive. The Department of Global Communications (U.N.) announced their drive to mobilize global cooperation in science-based COVID-19 responses, "The United Nations is mobilizing international cooperation to harness the power of science to tackle the coronavirus pandemic, while also working with partners to explore innovative crisis response tools."

Unlike the early months of the year, the second quarter showed the front lines to finally "catching up to the war efforts" with installments of these comprehensive containment measures:
  • a dedicated testing strategy & global data tracking
  • ample access to Covid tests and antibody testing
  • policy enforced education about preventive and safety guidelines
  • ample manufacturing of medical equipment and medicines
  • consistent PPE supply & distribution chains
  • trained critical care response personnel
  • lab research for therapeutics and vaccines




Other articles recently published in Prevention101.org

"The Power of Prevention of Covid-19 is in YOUR HANDS"
Source: MD Anderson Cancer Center
Watch how a blacklight reveals what improper hand washing can leave behind. According to Dr. Christina Le-Short of MD Anderson Cancer Center, "Cancer patients are at greater risk of developing complications from respiratory viruses... Effective hand-washing is your best defense against germs that cause the flu or Covid-19". 


Possible Health Hazards Behind the Mask
Source: NIOSH SCIENCE BLOG
Reports about Prolonged PPE Use by healthcare workers are aligned with health issues from abnormally elevated carbon dioxide (CO2) levels in the blood causing increased pressure inside the skull, nervous system changes, cardiovascular effects and reduced tolerance to lighter workloads that may lead to possible dizziness, hyperventilation and dehydration. View the report by the CDC about the many physiological effects of breathing increased concentrations of CO2 and the effects of failing overused respirator masks: See complete article



Suggested Safety Measures for Covid Prevention in Medical Offices  From respirators to hand sanitizers to regular use of hospital-grade disinfectants, the medical community is trusted to apply and set standards when it comes to safety measures, risk prevention strategies and sanitizing efforts. This new article offers a collective set of smart and sensible safety ideas from a group of doctors in your area. Promoting SAFETY GUIDELINES in any health practice is everyone's duty in our community.  See complete article




References:
1) Some doctors moving away from ventilators for virus patients: https://apnews.com/8ccd325c2be9bf454c2128dcb7bd616d



2) Global economy to be worst hit since Great Depression: Gita Gopinath, Chief Economist, IMF
















6) Study: 88% of coronavirus patients on ventilators died in NY




7) Coronavirus patients on ventilators are unusually likely to die, causing some doctors to change strategy




8) Texas Medical Center Data: https://www.tmc.edu/




9) Nearly 9 in 10 COVID-19 patients who are put on a ventilator die, New York hospital data suggests




10) Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area




11) Center for American Progress: Removing Barriers for Immigrant Medical Professionals Is Critical To Help Fight Coronavirus  https://www.americanprogress.org/issues/immigration/news/2020/04/02/482574/removing-barriers-immigrant-medical-professionals-critical-help-fight-coronavirus/




12) UN Foundation: HOW THE WORLD’S SCIENTISTS, DOCTORS, AND NURSES ARE UNITING TO FIGHT COVID-19  https://unfoundation.org/blog/post/how-worlds-scientists-doctors-and-nurses-uniting-fight-covid-19/




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Thursday, June 25, 2020

UNION OF SCHOLARS FORMULATE COVID TREATMENT PROTOCOL



With a confirmed global count of 9.27+ Million cases and 470,000+ deaths,  the world continues its desperate search for a treatment that will save the lives of COVID-19 patients who come into the ER or hospital with low oxygen levels or struggling to breathe.  Where the more popular treatment for patients in ICU is the use of ventilators, a reported 80-85% of Covid-19 patients on ventilators in New York end up dying (Associated Press and state and city officials).

A founding union of experts discuss the MATH+
protocol in this widely shared video: SEE LINK
M.A.T.H.+ ESSENTIALS:
Recently, a group of scholars specializing in critical care developed what appears to be an effective treatment protocol using a combination of medicines that is having remarkable success in hospitals that have adopted its use. According to the critical care physicians applying this formula, MATH+ manages multiple facets of the illness, such as sepsis, inflammation, severe clotting, and acute respiratory distress syndrome (ARDS), all complications known to arise from CoronaVirus infection. This protocol is designed to counter the body’s overwhelming inflammatory response to the virus as it is this hyper‐inflammation, not the virus itself, that damages the lungs and other organs, and ultimately leads to multi-organ failure and death. (To view the complete video of the founding union of experts discuss the MATH+ protocol, visit: www.covid19criticalcare.com)

The corticosteroid Methylprednisolone is a key component, based on large studies that have proven its effectiveness in prior viral pandemics‐ and whose potency is significantly increased when administered intravenously with high doses of the antioxidant Ascorbic acid (Vitamin C). Thiamine (Vitamin B1) is given to optimize cellular oxygen utilization and energy consumption, protecting the heart, brain, and immune system and the anticoagulant Heparin prevents (or breaks up) blood clots that increasingly appear as illness worsens. The + represents other supportive treatments by the administering doctor for patients who present other pre‐existing conditions (as needed). The group also plans to add or change components and dosing as published  medical  literature evolves.


PROVEN SUCCESS FROM THE FRONT LINES
This segment is based on a recent interview with Dr. Joseph Varon, Chief of Clinical Care at the United Memorial Medical Center in Houston, TX.  Dr. Varon introduces the MATH+ treatment solution from the Covid Unit of one of America's latest CoronaVirus epicenters.




THE JUNE SPIKE OF HOUSTON
According to the Texas Medical Center data, COVID-19 cases escalated from 267 in week 10 (5/31) to 962 in week 13 (6/21). "I've had the worst 48 hours of the last 84 days. I have received more patients over the last two weeks than in the last 10 weeks [totalled]. As the state opened up, people get crazy‐‐ this includes Memorial day weekend and last week's protest and mass gatherings. Out of all this, my ward is getting a flood of patients. I have tested more than 55,000 people for Covid in the Houston metropolitan area‐‐ and out of those 55,000, 10.5% are Covid positive. And these numbers in Texas are still going up."

Dr. Varon attributes the current increase in case numbers to the lack of social distancing among the general public as the state's lock‐down is released. "I'm seeing more cases now than I have ever seen. So I have to trust our data based on all that work that we have done as a group. The problem is that (at least) in Texas, when people got told that they can go out to restaurants, they act as if CoronaVirus is over! There is no social distancing, no masks... nothing. The virus is very unique and what we're seeing now, the severity of illness for us is increasing from all these mass gatherings... but also the people‐‐ they don't give too much attention to the virus. By the time they come to us, it's often too late. MATH+ works beautifully when you start early. So the sooner I can start you off, the better off you are!"

REPLACING THE VENTILATOR
Medical data from UMMC Covid Patients
Treated with MATH+: Click to Enlarge
Countless news reports and researchers are now showing a significant percentage (75‐85%) of ventilated patients are ending in death. Interviews with medical experts state that patients who are ventilated typically have critical or dire conditions‐ whereby ventilators are not the cause of death.

According to the Journal of American Medical Assoc., "In (a) case series that included 5700 patients hospitalized with COVID‐19 in the New York City area, the most common comorbidities were hypertension, obesity, and diabetes. Among patients who were discharged or died (n = 2634), 14.2% were treated in the intensive care unit, 12.2% received invasive mechanical ventilation, 3.2% were treated with kidney replacement therapy, and 21% died."

"When the pandemic started, my partner who owns a hospital was going crazy, trying to get ventilators. When we started working with MATH+, we actually changed the whole concept of treatment. Out of the last 70 patients that I've had with severe Covid, only two have required ventilators.  Why? Because I can manage most of the patients with high flow nasal cannula (HFNC), which are special devices that can provide large amount of oxygen comfortably to patients without having to put them on it on a respirator. Now this is not what's happening across the U.S. a lot of people are still using ventilators. A lot of people don't believe that when we tell them, once you put a patient on a mechanical ventilator, we're pretty much giving them more than 80% chance of dying. Information changes every day. In early March, I was probably thinking about ventilating a lot of people, but when I saw that MATH+ was working fabulously, that changed everything. And when we started to give them all these corticosteroids, ascorbic acid and the Heperin... they get well!"


"MATH+ Saved My Life" - In March, 2020, Jeffrey Boney of Houston, TX had fallen critically ill from the CoronaVirus and checked into critical care at United Memorial Medical Center.  Dr. Joseph Varon, frontline physician saved Mr. Boney through the use of FLCCC’s MATH+ protocol. (see Mr. Boney's video)



PAVING THE WAY TO GLOBAL ACCEPTANCE- ONE PATIENT AT A TIME
By: Dr. Joseph Varon

Dr. Paul Marik and I have been working together for close to 30 years. Since the middle of 2017, we've been working very closely on the H.A.T. protocol, (Hydrocortisone, Ascorbic Acid and Thiamine) and we enrolled more than 1500 patients together. By the time the pandemic came around, that's when I met with Dr. Umberto Meduri (the world's Guru on corticosteroids) and educated us all on Methylprednisone as a better choice. Then other specialists and researchers came aboard like Dr. Jose Iglesias and Dr. Pierre Kory‐‐ the group just came together, all from video conferencing.

Like anything else in life, every time a new therapeutic intervention comes in, it's usually met with a lot of resistance. Oddly enough, I'm getting a lot of international acceptance. Domestically, acceptance is not there yet. We are still having issues of people here who are just afraid‐ of giving steroids because they think that patients are going to get worse. They're stuck on the idea of intubating everybody. Now, in all fairness, when I am in my regular ICU, if you sneeze, I will intubate you. I'll put you on a respirator. But if I am on the Covid unit, I will do whatever it takes to prevent you from getting ventilated.

Covid‐19 is a very liquid illness because of its ability to keep changing. What I'm doing today is not what I was doing 10 weeks ago. We're in June now, and we are in the process of (still) learning more about the disease... and (with concepts like MATH+), we are trying to implement things that are easy to adopt by everybody. As of today, in my hospital, we have a 96.7 percent success rate with MATH+ . When you look at the data from Dr. Marik’s hospital and some of the other members of FLCCC, we're talking about a 95%, success rate among everybody. That's by far the best therapeutic intervention that is out there for coronavirus.

(End of Part 1)
For complete information about the MATH+ treatment protocol, visit: www.covid19criticalcare.com

...................................................................................................................................................................

VIEWPOINTS

'The Front Line Critical Care formula of early steroids (methylpred), anticoagulation (heparin) and supplements (ascorbic acid) MATH+ transformed our care of COVID patients and has saved many many lives.  We have been using MATH + for months, successfully.  The Front Line's are to be commended for realizing that the virus causes an inflammatory disease with available therapies.  While a pandemic raged the Front Line created a treatment for COVID 19 through first principles, reading, listening and collaborating.  Skills and a clarity of thought that all doctors aspire to.  MATH+ has been available for months and is a game changer." - Dr. Peter Tofts (Baptist Memorial) MBBC Medical ICU director, Associate Professor Internal Medicine


"The incredible work that has emerged from the group of scholars working on the MATH+ formula for patient care reminds me of the importance of collaboration in medicine.  This treatment formula was designed with patient care in mind, during an unprecedented time in our history.  The formula has clearly been shown to be an effective treatment to combat the virus.  The combination of corticosteroids, ascorbic acid and the Heperin has effectively been shown to reduce severity of patient symptoms and greatly reduce the need for the ventilator.  This is certainly a step forward in treatment options for COVID19 patients."   - Dr. Noelle Cutter (Molloy College | Associate Professor of Biology and Chemistry) 
"I find the M.A.T.H.+ protocol to be a very intelligent approach to combining known proven treatments of COVID-19 into one complete protocol. From the experience of over 12.7 million worldwide cases and over 566,000 deaths, we learned COVID-19 can lead to an overwhelming inflammatory response to the virus which can lead to severe morbidityy. M.A.T.H.+ hits different points in the body’s over-reactive immune response; Methylprednisolone (a corticosteroid) decreases the body’s inflammatory response. Ascorbic acid (vitamin C) and Thiamine (vitamin B1) optimizes cellular oxygenation protecting the vital organs and optimizes the immune system. Finally Heparin (anticoagulant) stops the known hypercoagulation which leads to strokes and organ failure as the organs lose their vital blood supply. I am truly very impressed with the combined scholarship to create this M.A.T.H.+ protocol. It will surely help physicians save lives." - Stephen A. Chagares, MD, FACS

 "In global pandemics with changing guidelines such scholarly articles based on facts and effective treatment options provide useful insights. While  world awaits for vaccine and effective treatment for Covid, existing proven treatment regime like "MATH+"  provides evidence based guidance to fight the current  pandemic to majority of world deprived of  access to cutting edge medicines and vaccines immediately." - Smita Dhumal, MD, MS, CCRC / Clinical Trial Manager at Amgen

 "A group of scholars, specializing in critical care has developed MATH+ protocol, which reveals to be a fantastic treatment combating the virus Covid19 until a vaccine has been found. This, by fighting the hyper-inflammation that damages the lungs, with a less expensive treatment, and thus, affordable to everybody. This group of scholars have demonstrated how important is team work between scholars and teachers, and Dr. Varon reported that MATH+ protocol has provided until 96.7 percent success rate in his hospital."  - Sergio Marcucci, DO, MSc, DHSc / Private Practice of osteopathic medicine (Luxembourg), A. T. Still University College of Graduate Health Studies
"As a health coach one of my goals is to help my clients reduce inflammation in their body. Chronic Inflammation causes the body’s inflammation response to eventually damage the body’s healthy cells, tissues and organs.  Ventilators being used are only enabling COVID-19 patients to breathe however a protocol such as MATH plus that uses a combination of medicines such as Ascorbic Acid (Vitamin C) and Thiamine to protect the heart, brain and immune system is battling the chronic inflammation that leads to failure of organs. It’s a functional approach and provides a chance of survival as well as a possibility of counteracting future disease."  - Sonia Bhatia, MBA, INHC (www.beinghealthylivingwell.com)

"To unite like minds toward a powerful goal (like saving lives) has always been a global effort worth pursuing.  This article about MATH+ was tremendous... it raised the bar of awareness as far as bringing out information that most people may not have heard about. It captivated me to read more about Dr. Varon, Dr. Marik and the entire group of doctors involved! As we are all quarantined and locked into the watching grim news, this is the BEST news I've read in months!"  - Carmen Regallo-Dewitt, PhD / Medical research/columnist for www.AwarenessforaCure.org | 
-------------------------------------------------------------------------------------------------------------------------





THE "COVID WAR"- FOUGHT BY A GLOBAL ALLIANCE OF SCIENTISTS
By: Adrian Barrios

June 24, 2020- Months into the CoronaVirus pandemic, the tally of efforts expended by government health agencies and professionals worldwide has been noted to significantly exceed any global campaign in history.  Economists tend to use war terms to help put the pandemic's containment efforts and collateral damage in perspective.  IMF's chief economist Gita Gopinath,  (in an April 15 news conference) stated that "the best case scenario, the world is likely to lose a cumulative $9 trillion in output over two years"- making this a global war 3x the fiscal size of World War II.

As with past wars, alliances were formed, industries were committed to task and scientists worldwide have united by sharing information toward this single directive. The Department of Global Communications (U.N.) announced their drive to mobilize global cooperation in science-based COVID-19 responses, "The United Nations is mobilizing international cooperation to harness the power of science to tackle the coronavirus pandemic, while also working with partners to explore innovative crisis response tools."

Epidemiology
Unlike the early months of the year, the second quarter showed the front lines to finally "catching up to the war efforts" with installments of these comprehensive containment measures:
  • a dedicated testing strategy & global data tracking
  • ample access to Covid tests and antibody testing
  • policy enforced education about preventive and safety guidelines
  • ample manufacturing of medical equipment and medicines
  • consistent PPE supply & distribution chains
  • trained critical care response personnel
  • lab research for therapeutics and vaccines

GLOBAL SOLIDARITY AGAINST THE PANDEMIC
"The COVID-19 pandemic has demonstrated the interconnected nature of our world – and that no one is safe until everyone is safe.  Only by acting in solidarity can communities save lives and overcome the devastating socio-economic impacts of the virus.  In partnership with the United Nations, people around the world are showing acts of humanity, inspiring hope for a better future." - United Nations

World medical conferences and international forums unite
multidisciplinary experts to continue global info-sharing
This pandemic has clearly illustrated that "Scientists by nature do not see borders or politics - only solutions", states Dr. Robert Bard, cancer diagnostics expert (NYC). "The spirit of teamwork is alive and well with this community- especially in a crisis. Historically, medical and scientific people have always raced to the front lines - always at the ready to pool resources and collaborate.  Like the domestic and international health associations, we continue to see some of the sharpest clinical minds in the world- including American teams that are now coming out with promising protocols to help end this pandemic.  To contain and eliminate this human threat means UNITING WITH SCIENCE AND WORKING TOGETHER ON A COORDINATED GOAL."

--------------------------------------------------------------------------------------------------------------------------


Other articles recently published in Prevention101.org

"The Power of Prevention of Covid-19 is in YOUR HANDS"
Source: MD Anderson Cancer Center
Watch how a blacklight reveals what improper hand washing can leave behind. According to Dr. Christina Le-Short of MD Anderson Cancer Center, "Cancer patients are at greater risk of developing complications from respiratory viruses... Effective hand-washing is your best defense against germs that cause the flu or Covid-19". 
Possible Health Hazards Behind the Mask
Source: NIOSH SCIENCE BLOG
Reports about Prolonged PPE Use by healthcare workers are aligned with health issues from abnormally elevated carbon dioxide (CO2) levels in the blood causing increased pressure inside the skull, nervous system changes, cardiovascular effects and reduced tolerance to lighter workloads that may lead to possible dizziness, hyperventilation and dehydration. View the report by the CDC about the many physiological effects of breathing increased concentrations of CO2 and the effects of failing overused respirator masks: See complete article
Suggested Safety Measures for Covid Prevention in Medical Offices  From respirators to hand sanitizers to regular use of hospital-grade disinfectants, the medical community is trusted to apply and set standards when it comes to safety measures, risk prevention strategies and sanitizing efforts. This new article offers a collective set of smart and sensible safety ideas from a group of doctors in your area. Promoting SAFETY GUIDELINES in any health practice is everyone's duty in our community.  See complete article




References:
1) Some doctors moving away from ventilators for virus patients: https://apnews.com/8ccd325c2be9bf454c2128dcb7bd616d

 2) Global economy to be worst hit since Great Depression: Gita Gopinath, Chief Economist, IMF
https://www.youtube.com/watch?v=rpiZ0DkHeGE

 3) W.H.O. CASE COUNT: https://covid19.who.int/?gclid=CjwKCAjw88v3BRBFEiwApwLevVNWB8VzRXQYzS6KGVe1QkdIdQ7P5G4SoXNIeYnTSKcIooGXKqbIzBoCnIkQAvD_BwE

 4) UChicago Medicine doctors see 'truly remarkable' success using ventilator alternatives to treat COVID-19 https://www.uchicagomedicine.org/forefront/coronavirus-disease-covid-19/uchicago-medicine-doctors-see-truly-remarkable-success-using-ventilator-alternatives-to-treat-covid19

 5) Ventilators: Helping or Harming COVID-19 Patients https://www.webmd.com/lung/news/20200415/ventilators-helping-or-harming-covid-19-patients#1

 6) Study: 88% of coronavirus patients on ventilators died in NY
https://www.syracuse.com/coronavirus/2020/04/study-88-of-coronavirus-patients-on-ventilators-died-in-ny.html

 7) Coronavirus patients on ventilators are unusually likely to die, causing some doctors to change strategy
https://www.independent.co.uk/news/coronavirus-ventilators-nhs-death-rates-china-wuhan-us-cases-a9458541.html

 8) Texas Medical Center Data: https://www.tmc.edu/

 9) Nearly 9 in 10 COVID-19 patients who are put on a ventilator die, New York hospital data suggests
https://www.livescience.com/coronavirus-ventilator-deaths-new-york.html

 10) Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area
https://jamanetwork.com/journals/jama/fullarticle/2765184

 11) Center for American Progress: Removing Barriers for Immigrant Medical Professionals Is Critical To Help Fight Coronavirus  https://www.americanprogress.org/issues/immigration/news/2020/04/02/482574/removing-barriers-immigrant-medical-professionals-critical-help-fight-coronavirus/

 12) UN Foundation: HOW THE WORLD’S SCIENTISTS, DOCTORS, AND NURSES ARE UNITING TO FIGHT COVID-19  https://unfoundation.org/blog/post/how-worlds-scientists-doctors-and-nurses-uniting-fight-covid-19/



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Monday, June 15, 2020

Respirators vs. Surgical Masks- What's the Difference?



Respirator vs. Surgical Mask - What's the Difference?
Written by: Dr. Robert Bard, MD, PC, DABR, FASLMS

 Months into the pandemic, we have confirmed that following CDC safety and prevention guidelines of wearing some approved form of face covering in public (or around others) is directly connected to the reduction and control of Covid-19 infection rates.  Time and time again, scientists and medical experts have valid proof that viruses travel through micro-droplets in the form of airborne contaminants. 


 Fact: ANY PPE is better than NO PPE!  The science of prevention states that measures toward a reduction in risk can greatly support life-saving others - and yourself.  Meanwhile, discerning the difference between face coverings, specifically MASKS vs RESPIRATORS can be useful in identifying which situation to use which type of mask. There is a significant difference between the two, and wearing one vs. the other provides differing results.

 The FDA defines a surgical mask as a loose-fitting, disposable device that creates a physical barrier between the mouth and nose of the wearer and potential contaminants in the immediate environment. If worn properly, a surgical mask is meant to help block large-particle droplets (NOT MICRO-DROPLETS), splashes, sprays, or splatter that may contain germs (viruses and bacteria), keeping it from reaching your mouth and nose. Surgical masks may also help reduce exposure of your saliva and respiratory secretions to others. While a surgical mask may be effective in blocking splashes and large-particle droplets, a face mask, by design, does not filter or block very small particles in the air that may be transmitted by coughs, sneezes, or certain medical procedures. Surgical masks also do not provide complete protection from germs and other contaminants because of the loose fit between the surface of the mask and your face.

 Meanwhile, an N95 respirator is an "efficient filter and a respiratory protective device designed to PROTECT YOU from airborne particles". Note that the edges of the respirator are designed to form a seal around the nose and mouth. Surgical N95 Respirators are commonly used in healthcare settings and are a subset of N95 Filtering Facepiece Respirators (FFRs), often referred to as N95s because it is actually rated by NIOSH to keep out or resist an estimated 95% of the harmful particulates in the air. [11]

KILLER BREATH CONTAINED GLOBALLY BY "MASKING TOGETHER"
by: Dr. Pierre Kory, M.D., M.P.A.

As far as respiratory protection, there has been quite a bit of confusion about MASK vs. RESPIRATOR in the early stages of COVID-19.  This was not just in the general public, but among many hospitals and infection control departments.  

 Initially, there was a great deal of reluctance in accepting the belief that COVID-19 could be transmitted via airborne means.  To explain this, viral infections (like the flu) are considered to be transmitted by what's called large droplets. When speaking, we all force out a little spittle with sizes ranging from visible to microscopic- such that you don't see leaving the mouth. The larger droplets do not travel far and do not “float” in the air and thus, social distancing is highly effective at preventing contact with a contaminated droplet reaching your oral mucosa or face. 

 However, AIRBORNE droplets are tiny, and can float and linger in the air for a period of time.  Airborne micro-droplets can be directly inhaled along with the virus without any person-to-person contact and even at large distances of separation. Just sharing the same room with an infected person, you can inhale the floating particles that they are exhaling, if they are not wearing a mask. This is what makes this infection different and much more dangerous than others. However, if an infected person near you is wearing a mask, even a simple one, the mask will trap the larger droplets so that smaller droplets are not created and will not become airborne. To achieve this protection, you need near 100% mask-wearing in confined indoor spaces.
Without near universal mask wearing, you get these "super spreader" events where someone went to choir practice and 52 of the 60 people there all came home sick. That's because tiny droplets were out in the air and floating. The only way to protect yourself from an airborne sized droplet emitted by a non-mask wearer is by you yourself wearing an N95 respirator. In such a situation, your N95 will filter out those tiny little particles from entering your airways. If fitted properly the N95 blocks 99% of the particles- and there's significant proof that the rates of infection among healthcare workers went drastically down after we started using N95 everywhere around COVID patients, none of whom were wearing any kind of mask which would have helped protect us.

Covid-19 : LaVision imaging technique shows how masks restrict the spread of exhaled air.  The primary way of person-to-person corona virus transmission is via aerosols or small droplets created by breathing, sneezing or coughing. The reach of exhaled air can be effectively reduced using a face mask as shown in the video. A simple Schlieren imaging technique is applied to visualize the air flow caused by a person breathing and coughing. Using a face mask the exhaled air flow is blocked reducing effectively the risk of infection. 

At a certain point, I was convinced that the entire world had to get an N95 mask to achieve sufficient protection from transmission within indoor spaces- but then I learned later that using a standard cloth mask (or a even a surgical mask) actually DOES work. And the reason why the data's showing such masks work is that if you look at a lot of the countries which successfully controlled the spread of this infection, all of those countries had mandated a hundred percent use of general face covering throughout the population. The way it works is, when two or more people are using a NON-N95 mask in a room, those large droplets would be trapped in the mask- not transmitting and not forming micro-particles that go airborne! By me wearing a mask, it actually protects YOU from me making those little airborne particles. 

 An effective scarf or home-made cloth mask may not have the same makeup as the N95, but they DO block about 60 to 70% of the particles. So they're not perfect, but what the data shows and what the epidemiological data shows from all those successful countries that controlled their cases is that as long as everybody wears a mask, any type of mask, the combined performance of two people  with those masks from each other actually reduces the risk of transmission to a very, very low level.

CONTRIBUTORS

ROBERT L. BARD, MD, PC, DABR, FASLMS
Advanced Imaging & Diagnostic Specialist
Dr. Bard received the 2020 nationally acclaimed Ellis Island Award for his lifetime achievement in advanced cancer diagnostic imaging. He co-founded the 9/11 CancerScan program to bring additional diagnostic support to all first responders from Ground Zero. His main practice in midtown, NYC (Bard Diagnostic Imaging- www.CancerScan.com) uses the latest in digital imaging technology and has been also used to help guide biopsies and in many cases, even replicate much of the same reports of a clinical invasive biopsy. Imaging solutions such as high-powered sonograms, Power Doppler Histogram, sonofluoroscopy, 3D/4D image reconstruction and the Power Doppler Histogram  are safe, noninvasive, and do not use ionizing radiation. 

PIERRE KORY, M.D., M.P.A.
Dr. Kory is Board Certified in Internal Medicine, Critical Care, and Pulmonary Medicine. He served as the Medical Director of the Trauma and Life Support Center at the University of Wisconsin where he was an Associate Professor and the Chief of the Critical Care Service. He is considered a pioneer and national/international expert in the field of Critical Care Ultrasound and is the senior editor of the widely read textbook “Point-of-Care Ultrasound” (winner of the President’s Choice Award for Medical Textbooks from the British Medical Association in 2015).  Most recently, Dr. Kory joined the emergency volunteer team during the early COVID-19 pandemic in NYC at Mount Sinai Beth Israel Medical Center. He is also a founding member of the Front Line COVID-19 Critical Working Group (flccc.net) composed of 5 critical care experts that devised the COVID-19 treatment protocol called MATH+. (www.covid19criticalcare.com/)
................................................................................................

POTENTIAL HEALTH RISKS BEHIND THE MASK
Introduction By: R. Christenson, MD (From: "Holding the Front Line with Zero"- an essay by a covid health responder)

During the worst 2 months of the pandemic in New York, I spent countless double-shifts in a constantly slammed Long Island Covid Unit, tending to what seemed like a never-ending avalanche of critical cases.  The vast majority of our medical team was stretched to the very max of their professional tolerance, where each traumatic situation bred severe anxiety, PTSD and a rising count of suicide.

 Exhaustion came in many forms; the drain on our mental composure ate away at our physical endurance as did the absence of sleep, zero nutrition plus the eminent fear and threat of death allaround us all. Add all that to the much reduced air supply from expired respirator use plus hedging on a number of serious complications from excessive CO2 intake - and you've got yourself the makings of some serious health conditions that may easily answer for what we simply call "burnout".


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The Physiological Burden of Prolonged PPE Use on Healthcare Workers during Long Shifts

Source: NIOSH SCIENCE BLOG/ CDCOriginal post on by Jon Williams, PhD; Jaclyn Krah Cichowicz, MA; Adam Hornbeck, MSN, APRN, FNP-BC, FNP-C; Jonisha Pollard, MS, CPE; and Jeffrey Snyder, MSN, CRNP.

Healthcare workers (HCW) and first responders often work long, physically and mentally exhausting shifts and are also required to wear personal protective equipment (PPE), which may include N95 filtering facepiece respirators (FFRs) elastomeric half-mask respirators, or powered air-supplied respirators (PAPRs). Particular features of PPE can impose a physiological (how the body normally functions) burden on the HCW which can be exacerbated by long work hours without adequate breaks for eating, hydration and self-care. HCWs should be provided regular opportunities to take breaks and a supportive environment to report symptoms related to their PPE use. For example, using an FFR for an extended period may cause dizziness (as well as other symptoms), which could compromise the worker, workplace, and patient safety. Dizziness is an important warning sign, as it can be caused by dehydration, hyperventilation (gasping for breath), elevated carbon dioxide [CO2] levels in the blood, low blood sugar, and anxiety, among other things.
When HCWs are working longer hours without a break while continuously wearing an N95 FFR, CO2 may accumulate in the breathing space inside of the respirator and continuously increase past the 1-hour mark, which could have a significant physiological effect on the wearer (Lim et al., 2006). Some of the known physiological effects of breathing increased concentrations of CO2 include:
  1. Headache;
  2. Increased pressure inside the skull;
  3. Nervous system changes (e.g., increased pain threshold, reduction in cognition – altered judgement, decreased situational awareness, difficulty coordinating sensory or cognitive, abilities and motor activity, decreased visual acuity, widespread activation of the sympathetic nervous system that can oppose the direct effects of CO2 on the heart and blood vessels);
  4. Increased breathing frequency;
  5. Increased “work of breathing”, which is result of breathing through a filter medium;
  6. Cardiovascular effects (e.g., diminished cardiac contractility, vasodilation of peripheral blood vessels);
  7. Reduced tolerance to lighter workloads.


Disclaimer: All content from "the above article (The Physiological Burden of Prolonged PPE Use on Healthcare Workers during Long Shifts" ) is republished in this associated blogsite / newsletter from its original source (NIOSH/CDC Science Blog) and is done so with express permission from NIOSH/CDC and is in compliance with the source's agency regulations. Whereas use of any and all materials, information and links to the materials on the CDC [Centers for Disease Control and Prevention], ATSDR or HHS [Health and Human Services] websites, does not imply endorsement by CDC, ATSDR, HHS or the United States Government of this publication, the NY Cancer Resource Alliance, IntermediaWorx Educational Publications and other producers/publishers herein. 
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UV-C Light is used to disinfect & extend PPE life for reuse
UVC and the Coronavirus
By: Dr. Robert L. Bard & Lennard Gettz

A rising trend in hospital disinfecting (as well as in commercial areas and public institutions) is the installation and use of UV-C disinfecting technology. From small 8" x 10" boxes that extend the life of face masks in the healthcare field, to 8-foot transportable setups that fully sanitize hospital recovery and surgical rooms to (lately) subway trains covering a daily chemical-free sanitizing program.  Controlling infections with UV-C is fast earning public acceptance as a low-risk, non-chemical solution with significantly proven effectiveness.

Hospitals that use UV-light disinfection typically applies this technology as a 2nd step to cleaning and disinfecting measures.  This process is recognized by clinical infection control professionals and agencies to significantly mitigate infection risks associated with environmentally mediated transmission routes. (see complete article)


 ...............................................................................................................................................................................................

RESOURCE 1: REPORTING BOGUS RESPIRATORS (part 1)
By: Stephanie Stevens (CDC / NIOSH / OD)
According to Megan Casey, MPH, a nurse epidemiologist in NIOSH’s Personal Protective Technology Laboratory: Coronavirus is thought to spread through respiratory droplets produced when an infected person coughs or sneezes, but some medical procedures could potentially suspend virus particles in the air that healthcare providers are breathing. Wearing appropriate respiratory protection is a vital line of defense during these procedures. Counterfeit respirators can compromise the safety of anyone who uses them, including healthcare providers.

NIOSH receives reports of possible counterfeit respirators through a number of channels.This includes reports from manufacturers who are trying to protect the integrity of their own NIOSH approval. We may also be contacted by purchasers and users who have concerns about product or marketing materials. NIOSH staff may also identify instances of counterfeits or misleading information, including through web searches or from reports from stakeholders.  

When NIOSH becomes aware of counterfeit respirators or those misrepresenting NIOSH approval on the market, these respirators are posted online to alert users, purchasers, and manufacturers. As per our regulation, NIOSH only has authority over companies that hold a NIOSH approval. If the devices are not approved by NIOSH, we have no authority over them. We can only report these issues on our Trusted Source webpage for Counterfeit Respirators/Misrepresentation of NIOSH-Approval.


Resources to help identify counterfeit respirators:


Also see our expanded feature: The "Wild West" PPE Industry + A special feature on COUNTERFEIT RESPIRATORS


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SUGGESTED SAFETY GUIDELINES FOR MEDICAL OFFICES

Copyright © 2020- IntermediaWorx Inc. Educational Publications & NY Cancer Resource Alliance


As essential health and medical service providers, our community looks to us to set the standards when it comes to implementing safety measures, risk prevention strategies and sanitizing efforts.  We are all in the same fight to control the spread of pathogens and to preserve the health of our patients and our staff.  These same priorities align with our commitment to share these top recommended protocols for HEALTH & SAFETY which we assembled from a wide survey of safety‐minded colleagues. We urge you to review and consider these safety measures for your office.  Only together can we continue 'flattening the curve' and win this global health crisis- one office at a time!


1) BY APPOINTMENT ONLY:    As private practices are now beginning to re-open on a cautiously limited and adjusted schedule, communicate with your patients that you are officially open for in-person patient care and your new office hours. Adjusted scheduling allows you to better spread out all appointments for better crowd control and allows your staff time to disinfect and clean between patients. Also, emphasize NO WALK-INS.

2) TEMPERATURE CHECKS AT THE DOOR: More and more businesses and professional practices are now requiring temporal temperature checks at the door as an essential public safety measure.  The doorway is a major point of contact with the public at large- and one of your first lines of defense, starting with temperature screenings. Also, you can suggest all patients to check their temperature prior to traveling to your office - and stay home if they have above 101 degree reading.

3) PATIENTS ANNOUNCE THEMSELVES UPON ARRIVAL: When the patient reaches your facility for their appointment, request that they announce themselves via phone from outside. This gives your staff a chance to adjust in case the office is backed up- or if you can see them earlier. If possible, encourage patients to wait outside the building until their time is ready.

4) THE "NEW" WAITING ROOM: More and more doctors’ offices are now reducing the number of seats, and others are even eliminating their waiting rooms altogether.  Waiting rooms have been recognized as a potential ground for sharing bacteria and viral pathogens.  Reducing the wait capacity to the least number of patients (ONE or TWO max) is crowd-control and supports social distancing. 



Brought to you in part by the NY Cancer Resource Alliance and the Advocacy for Professional Safety, publishers of Prevention101.org

REFERENCES-
2) Visual Detection of Bacteria and Microbes;  https://aabme.asme.org/posts/device-quickly-detects-live-bacteria-for-life-saving-diagnosis

 3) Acute Oxygen Therapy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1113909/

 4) Healthcare suggers from PTSD... https://ohsonline.com/Articles/2020/05/19/Healthcare-Workers-Suffer-from-PTSD-and-Burnout-During-COVID19.aspx?Page=3

 5) The Physiological Burden of Prolonged PPE Use on Healthcare Workers during Long Shifts  https://blogs.cdc.gov/niosh-science-blog/2020/06/10/ppe-burden/

 6) Compliance Safety and Health Officers (CSHOs) for enforcing the Respiratory Protection standard: https://www.osha.gov/memos/2020-04-24/enforcement-guidance-decontamination-filtering-facepiece-respirators-healthcare

7) Study: Think Twice About Reusing KN95 or Surgical Masks- https://www.medpagetoday.com/infectiousdisease/infectioncontrol/87077?xid=nl_popmed_2020-06-16&eun=g1405490d0r&utm_source=Sailthru&utm_medium=email&utm_campaign=DailyUpdate_061620&utm_term=NL_Daily_Breaking_News_Active

 11) https://www.fda.gov/medical-devices/personal-protective-equipment-infection-control/n95-respirators-surgical-masks-and-face-masks

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